Ofterdingen and Kropotkin

Prozac, the antidepressant taken by 40 million worldwide does not work and nor do similar drugs, according to a major review that examined all available data on the drugs, including results from clinical trials that the manufacturers chose not to publish at the time. (...) It appeared that patients had improved, but those on a placebo improved just as much as those on the drugs. The only exceptions were the most severely depressed patients, said the authors, Prof Irving Kirsch from the department of psychology at Hull University and colleagues in the US and Canada.

Guardian Weekly, 29.02.08, p. 7